How Does Medical Marijuana Work?

Medical marijuana contains active chemical compounds called phytocannabinoids that interact with a distinct physiological system known as the Endocannabinoid System. This system is comprised of endogenous cannabinoids, cannabinoid receptors, and regulatory enzymes. The endogenous cannabinoids and their receptors are found throughout the body: primarily in the nervous system and the immune system, but also in the gastrointestinal, endocrine, hematopoetic systems and more. Human and animal studies demonstrate the role of the endocannabinoid system in a wide variety of physiologic processes and this ubiquity of the endocannabinoid system suggests the possibility of multiple therapeutic roles for medical marijuana.

We’re Here To Help You

Our staff is here to help you with your questions. Contact our physician support team if you want to learn more about our company, become an ordering physician or discuss the benefits of medical marijuana.


First and foremost, Curaleaf offers compassion and understanding for your medical condition, and total support for the courage you show in fighting for a better life. We’re here to help by providing:

Curaleaf’s management team is comprised of entrepreneurs and seasoned professional with experience in health care, financial services, retail, and non-profits.
We were one of the first few groups to receive their Approval for Retail Sales during the state’s 2015 application process, and received the 2nd highest score in the state back in 2013.
Transparency from seed to sale means consistency, potency, safety assurance, and exceptional quality that patients and doctors can trust.

Physician Resources

Guidance for Physicians Regarding the Medical Use of Marijuana

Review the document produced by DPH to provide physicians

MMJ Online Registration System information

How to Register with the Medical Use of Marijuana Program: Instructions for Physicians

Frequently Asked Questions

How can I become a qualified physician?

DPH provides the following guidance to physicians regarding the Medical Use of Marijuana.

What are Qualifying Conditions?

In the state of Massachusetts you must have been diagnosed by a licensed physician as having a “debilitating medical condition.”   As outlined in the Act for the Humanitarian Medical Use of Marijuana, Section 2(C), the term “debilitating medical condition” includes the following:

  • ALS (Amyotrophic Lateral Sclerosis)
  • Cancer and malignant tumors
  • Crohn’s Disease/Ulcerative Colitis (UC)
  • Glaucoma
  • Hepatitis C
  • Positive status for human immunodeficiency virus (HIV)
  • Acquired immune deficiency syndrome (AIDS)
  • MS (Multiple Sclerosis)
  • Parkinson’s Disease

Section 2(C) also accounts for “other conditions as determined in writing by a qualifying patient’s physician.”  These conditions may include, but are not limited to, the following:

  • Anorexia
  • Anxiety
  • Chronic Back Pain
  • Depression
  • Insomnia
  • RA (Rheumatoid Arthritis)

Have Questions?

A Curaleaf expert is happy to help.